Oliver Vöcking*, K. Van Der Meulen#, M.K. Patel, J.K. Famulski*Zebrafish anterior segment mesenchyme progenitors are defined by function of tfap2a but not sox10Differentiation, Volume 130, 2023, Pages 32-42, https://doi.org/10.1016/j.diff.2022.11.002
# graduate student, * co-first author


Vöcking O, Famulski JK. A temporal single cell transcriptome atlas of zebrafish anterior segment development. Sci Rep. 2023 Apr 6;13(1):5656. doi: 10.1038/s41598-023-32212-4.PMID: 37024546


Sheppard MB, Smith JD, Bergmann LL, Famulski JK. Novel SMAD3 variant identified in a patient with familial aortopathy modeled using a zebrafish embryo assayFront Cardiovasc Med. 2023 Feb 28;10:1103784. doi: 10.3389/fcvm.2023.1103784. eCollection 2023.PMID: 36926042


Vöcking O, Famulski JK. Single cell transcriptome analyses of the developing zebrafish eye - perspectives and applicationsFront Cell Dev Biol. 2023 Jun 29;11:1213382. doi: 10.3389/fcell.2023.1213382. eCollection 2023.





Piedade WP and Famulski JK. E3 ubiquitin ligase-mediated regulation of vertebrate ocular development; new insights into the function of SIAH enzymesBiochem Soc Trans. 2021 Feb 26;49(1):327-340. doi: 10.1042/BST20200613.​




Warlen, P. Piedade.#* Titialii, K#*, Morris A. and J.K Famulski. 2020. Proteasome-Mediated Regulation of Cdhr1a by Siah1 Modulates Photoreceptor Development and Survival in ZebrafishFront Cell Dev Biol. 2020;8:594290. doi: 10.3389/fcell.2020.594290. eCollection 2020. 

# graduate student, * co-first author


Kristyn Van Der Meulen#, Oliver Vocking, Megan Weaver# Nishita Meshram and J.K. Famulski. 20202. Spatiotemporal characterization of anterior segment mesenchyme heterogeneity during zebrafish ocular anterior segment development. Frontiers: Cell and Developmental Biology May27, 2020. https://doi.org/10.3389/fcell.2020.00379

# graduate student 


Megan Weaver#, Warlen Piedade#, Nishita Meshram and J.K. Famulski. 2020 Hyaloid vasculature and mmp2 activity play a role during optic fissure fusion in zebrafish. Scientific Reports June 23, 2020. https://rdcu.be/b47PK.

# graduate student 




Warlen, P. Piedade#, Veith, S$. and J.K Famulski. Ubiquitin-mediated proteasome degradation regulates optic fissure fusion. 2019,  Biology Open, June 17, 2019.    http://bio.biologists.org/lookup/doi/10.1242/bio.044974.

# graduate student   $ undergraduate student


Nicholas, Carrara*#, Megan Weaver*#, Warlen Piedade*#, Oliver Vocking and J.K. Famulski. Temporal characterization of optic fissure basement membrane composition suggests nidogen may be an initial target of remodeling. 2019.  Developmental Biology, online April 26, 2019 https://doi.org/10.1016/j.ydbio.2019.04.012    

* co-first author   # graduate student




Jennifer C. Hocking*, Jakub Famulski*, Sonya Widen, Sophie Koch, Tara Stach, Omri Weiss, Adi Inbal, Ordan J. Lehmann, Andrew J. Waskiewicz. 2018. Superior coloboma: a novel disease originating from a newly discovered feature of ocular development. March 9, 14(3) PLoS Genetics    

*co-first author




Qin L, Favis N, Famulski J, Evans DH. Evolution of and evolutionary relationships between  extant vaccinia virus strainsJ Virol. 2015 Feb;89(3):1809-24.


Devinderjit Kaur, Nathan Westcott, Jakub K. Famulski, Kinjal Patel, Dawn Macdonald,Howard Hang, Gordon K.T. Chan. 2015. A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores. 208(7):881-96, Journal of Cell Biology.




Sameer D. Pant, Lindsey D. March, Curtis R. French, Jakub K. Famulski, Ordan J. Lehmann, Andrew J. Waskiewicz. Zebrafish Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants. Aug 28;54(8):5871-9 Invest Ophthalmol Vis Sci.


Holly B*, J.K. Famulski*, Widen SA* and A. Waskiewicz. 2014. Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development. Jan 20. S0012-1606(14), Developmental Biology

          *co-first authors




Pillay L., Fleisch V, Leighton P, Famulski J, Cheng C, March L, Ritzel G, Allison T, and A. Waskiewicz. 2013. Evaluating the mutagenic activity of targeted endonucleases containing a Sharkey FokI cleavage domain variant in zebrafish. 2013 Sep;10(3):353-64. Zebrafish


Mika Asai-Coakwell, Lindsey March, Xiao Hua Daia, Michele DuValb, Irma Lopezf, Curtis R. Frencha, Jakub Famulski, Elfride De Baereg, Peter J. Francish, Periasamy Sundaresani, Yves Sauvéa,c,  Robert K. Koenekoopf, Fred B. Berryd,e, W Ted Allisonb,d, Andrew Waskiewiczb†, Ordan J. Lehmann. 2013. Contribution of Growth Differentiation Factor 6 dependent cell survival to early onset retinal dystrophies.  1;22(7): 1432-42, Human Molecular Genetics.


Famulski J.K., D.J. Solecki. 2013.New spin on an old transition: epithelial parallels in neuronal adhesion control. 36(3):163-73. Trends in Neurosciences. 




Vos L.J., Famulski J.Kand G.K. Chan. 2011. hZwint-1 bridges the inner and outer kinetochore: Identification of the kinetochore localization domain and the hZw10 interaction domain. 15;436(1):157-68 Biochem J.


Famulski J.K., Vos L.J., Rattner J.B and G.K. Chan. 2011. Dynein/Dynactin-Mediated transport of kinetochore components off kinetochores and onto spindle poles induced by Nordihdroguaretic AcidPLoS One 6(1):e:16494




Famulski J.K, Trivedi N, Howell D, Yang Y, Tong Y, Gilbertson R, and D.J. Solecki. 2010. Siah regulation of Pard3 controls neuronal adhesion during germinal zone exit. Science 330(6012):1834-1838 




Kim S., S.Y. Park, H. Yong, J.K. Famulski, S. Chae, J.-H. Lee, C.-M. Kang, H. Saya, G.K. Chan*and H. Cho*. 2008. HBV X protein targets hBubR1, which induces dysregulation of the mitotic checkpoint.*co-corresponding authors Oncogene, 27(24):3457-64.


Famulski J.K., Vos L.J., Sun X.J. and G.K. Chan. 2008. Stable hZW10 residency at kinetochores, mediated through hZwint-1 interaction, is essential for mitotic checkpoint functionJournal of Cell Biology, 180:507-520.


Famulski J.K., G.K. Chan. 2007. Aurora B kinase-dependent recruitment of hZW10 and hROD to tension-less kinetochoresCurrent Biology 17, 2143–2149.


Huang H., Feng J., Famulski J., Rattner J.B., Liu S.T., Kao G.D., Muschel R., Chan G.K.T., T.J. Yen. 2007. Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsJ. Cell Biology 17:413-424.


Vos LJ, Famulski JK, Chan GK.  How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.  2006. Biochem Cell Biol  84(4):619-630











All Rights for the images reserved to mugley photostream from flickr, if you keep them,please keep the credit.


T: 859-218-3540 |  jakub.famulski@uky.edu

Famulski Lab zebrafish retinal development