* equal contributors
53. Inoue T, Zhang P, Zhang W, Goodner-Bingham K, Dupzyk A, DiMaio D, Tsai B Gamma-secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection. J. Cell Biology. (in press)
52. Dupzyk A, Tsai B Bag2 is a component of a cytosolic extraction machinery that promotes membrane penetration of a nonenveloped virus. J. Virol.
51. Ravindran MS, Spriggs CC, Verhey KJ, Tsai B Dynein engages and dissasembles cytosol-localized SV40 to promote infection. J. Virol.
50. Arunagiri A, Haataja L, Cunningham CN, Shrestha N, Tsai B, Qi L, Liu M, Arvan P Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes Annals of the New York Academy of Sciences.
49. Inoue T, Tsai B. Regulated Erlin-dependent release of the B12 J-protein promotes ER membrane penetration of a non-enveloped virus. PLoS Pathog.
48. Ravindran MS*, Engelke MF, Verhey KJ, Tsai B*. Exploiting the kinesin-1 molecular motor to generate a virus membrane penetration site. Nat Commun.
47. Dupzyk A, Williams JM, Bagchi P, Inoue T, Tsai B. SGTA-dependent regulation of Hsc70 promotes cytosol entry of SV40 from the ER. J Virol.
46. Qi L, Tsai B, Arvan P. New Insights into the Physiological Role of ER-associated degradation. Trends Cell Biol.
45. Cunningham CN*, He K*, Arunagiri A, Paton AW, Paton JC, Arvan P, Tsai B. Chaperone-driven degradation of a misfolded proinsulin mutant in parallel with restoration of wild-type insulin secretion. Diabetes.
44. Bagchi P, Inoue T, Tsai B. EMC1-dependent stabilization drives membrane penetration of a partially destabilized non-enveloped virus. eLife.
43. Dupzyk A, Tsai B. How polyomaviruses exploit the ERAD machinery to cause infection. Viruses.
42. Ravindran MS*, Bagchi P*, Cunningham C, Tsai B. Opportunistic intruders: Viruses orchestrate the ER function to cause infection. Nat Rev Micro.
41. Williams JM, Tsai B. Intracellular trafficking of bacterial toxins. Curr Opin Cell Biology.
40. Ravindran MS, Tsai B. Viruses utilize cellular cues in distinct combination to undergo systematic priming and uncoating. PLoS Pathog.
39. Inoue T, Tsai B. The Grp170 nucleotide exchange factor executes a key role during ERAD of cellular misfolded clients. Mol Biol Cell.
38. Haataja L, Manickam N, Soliman A, Tsai B, Liu M, Arvan P. Disulfide mispairing during proinsulin folding in the Endoplasmic Reticulum. Diabetes.
37. Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber R, Shen X, Lee A, Iwawaki T, Paton A, Paton J, Fang D, Tsai B, Yates J, Wu H, Kersten S, Long Q, Duhamel G, Simpson KW, Qi L. IRE1α is an endogenous substrate of Endoplasmic Reticulum-associated degradation. Nat Cell Biol.
36. He K*, Ravindran MS*, Tsai B. A bacterial toxin and a nonenveloped virus hijack ER-to-cytosol membrane translocation pathway to cause disease. Crit Rev Biochem Mol Biol.
35. He K*, Cunningham C*, Manickam N, Liu M, Arvan P*, Tsai B*. PDI reductase acts on Akita mutant proinsulin to initiate retro-translocation along the Hrd1/Sel1L-p97 axis. Mol Biol Cell.
34. Ravindran MS, Bagchi P, Inoue T, Tsai B. A non-enveloped virus hijacks host disaggregation machinery to translocate across the Endoplasmic reticulum membrane. PLoS Pathog.
33. Inoue T, Dosey A, Herbstman JF, Ravindran MS, Skiniotis G, Tsai B. ERdj5 reductase cooperates with protein disulfide isomerase to promote SV40 Endoplasmic reticulum membrane translocation. J Virol.
32. Williams JM, Inoue T, Chen G, Tsai B. The NEF Grp170 and Sil1 induce cholera toxin release from BiP to enable retrotranslocation. Mol Biol Cell.
31. Inoue T, Tsai B. A nucleotide exchange factor promotes ER-to-cytosol membrane penetration of the nonenveloped virus Simian virus 40. J Virol.
30. Bagchi P, Walczak CP, Tsai B. The ER membrane J protein C18 executes a distinct role in promoting simian virus 40 membrane penetration. J Virol.
29. Walczak CP, Ravindran MS, Inoue T, Tsai B. A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the Endoplasmic reticulum. PLoS Pathog.
28. Bernardi KM, Williams JM, Inoue T, Schultz A, Tsai B. A deubiquitinase negatively regulates retro-translocation of non-ubiquitinated substrates. MolBiolCell.
27. Moore P, He K, Tsai B. Establishment of an in vitro transport assay that reveals mechanistic differences in cytosolic events controlling cholera toxin and T-cell receptor-α retro-translocation. PLoS One.
26. Williams JM, Inoue T, Banks L, Tsai B. The ERdj5-Sel1L complex facilitates cholera toxin retro-translocation. Mol Biol Cell.
25. Inoue T, Tsai B. How viruses use the endoplasmic reticulum for entry, replication, and assembly. Cold Spring Harb Perspect Biol.
24. Walczak CP, Bernardi KM, Tsai B. ER-dependent redox reactions control ER-associated degradation and pathogen entry. Antioxid Redox Signal.
23. Inoue T, Tsai B. A large and intact viral particle penetrates the ER membrane to reach the cytosol. PLoS Pathog.
22. Walczak CP, Tsai B. A PDI family network acts distinctly and coordinately with ERp29 to facilitate polyomavirus infection. J Virol.
21. Bradbury FA, Tsai B. Functional versus decoy receptor-regulated entry of polyomaviruses. Future Virology.
20. Inoue T, Moore P, Tsai B. How viruses and toxins disassemble to enter host cells. Annu Rev Microbiol. (*equal contributors)
19. Goodwin E, Lipovsky A, Inoue T, Magaldi T, Edwards APB, Yates KE, Paton AW, Paton JC, Atwood W, Tsai B, DiMaio D. BiP and multiple DnaJ molecular chaperones in the endoplasmic reticulum are required for efficient SV40 infection. mBio.
18. Bernardi, KM, Williams JM, Kikkert M, van Voorden S, Wiertz EJ, Ye Y, Tsai B. The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation. Mol Biol Cell.
17. Moore P, Bernardi KM, Tsai B. The Ero1alpha-PDI redox cycle regulates retro-translocation of cholera toxin. Mol Biol Cell.
16. Tsai B, Qian M. Cellular entry of polyomaviruses. Curr Top Microbiol Immunol.
15. Qian M, Tsai B. Lipids and proteins acts in opposing manners to regulate polyomavirus infection. J Virol.
14. Tsai B, Inoue T. A virus takes an “L” turn to find its receptor. Cell Host Microbe.
13. Rainey-Barger EK, Mkrchian S, Tsai B. The C-terminal domain of ERp29 mediates polyomavirus binding, unfolding, and infection. J Virol.
12. Jiang M, Abend JR, Tsai B, Imperiale, MJ. Early events during BK virus entry and disassembly. J Virol.
11. Forster ML, Mahn J, Tsai B. Generating an unfoldase from thioredoxin-like domains. J Biol Chem.
10. Qian M, Cai D, Verhey KJ, Tsai B. A lipid receptor sorts polyomavirus from the endolysosome to the endoplasmic reticulum to cause infection. PLoS Pathog.
09. Erickson KD, Garcea RL, Tsai B. Ganglioside GT1b is a putative host cell receptor for the Merkel cell polyomavirus. J Virol.
08. Lam AD, Tryoen-Toth P, Tsai B, Vitale V, Stuenkel EL. SNARE-catalyzed fusion events are regulated by syntaxin1A-lipid interactions. Mol Biol Cell.
07. Bernardi KM, Forster ML, Lencer WI, Tsai B. Derlin-1 facilitates the retro-translocation of cholera toxin. Mol Biol Cell.
06. Rainey-Barger EK, Mkrtchian S, Tsai B. Dimerization of ERp29, a PDI-like protein, is essential for its diverse functions. Mol Biol Cell.
05. Tsai B (2007). Penetration of non-enveloped viruses into the cytoplasm. Annu Rev Cell Dev Biol.
04. Rainey-Barger EK, Magnuson B, Tsai B. A chaperone-activated non-enveloped virus perforates the physiologically relevant ER membrane. J Virol.
03. Low JA, Magnuson B, Tsai B, Imperiale MJ (2006). Identification of gangliosides GD1b and GT1b as receptors for BK virus. J Virol.
02. Forster LM, Sivick K, Park Y-N, Arvan P, Lencer W, Tsai B (2006). Protein disulfide isomerase-like proteins play opposing roles during retro-translocation. JCB.
01. Magnuson B, Rainey EK, Benjamin T, Baryshev M, Mkrtchian S, Tsai B. ERp29 triggers a conformational change in polyomavirus to stimulate membrane binding. Mol Cell.